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fallopia multiflora liver

Choi, S. G., Kim, J., Sung, N. D., Son, K. H., Cheon, H. G., Kim, K. R., and Kwon, B. M. Anthraquinones, Cdc25B phosphatase inhibitors, isolated from the roots of Polygonum multiflorum Thunb. Some medications are changed and broken down by the liver. 2006;26(3):181-183. It is in flower from September to October, and the seeds ripen from October to November. Some stimulant laxatives include bisacodyl (Correctol, Dulcolax), cascara, castor oil (Purge), senna (Senokot), and others. Do not take fo-ti if you are taking a medication that can harm the liver. Indianapolis, IN: First Data Bank 99.1-99. Fallopia multiflora has been widely studied as a result of its potential to combat the effects of aging. (check all that apply), What factors are most important to you? As a consequence, it is a requirement that listed medicines containing Fallopia multiflora for oral use to have the following warning on the product label: ‘Warning: Fallopia multiflora may harm the liver in some people. View abstract. CYP1A2 polymorphism in Chinese patients with acute liver injury induced by Polygonum multiflorum. It is one … 11th ed. Polygonum multiflorum, Helxine multiflorum, Pleuroptterus cordatus, Polygonum convolvulus, Polygonum … Some medications changed by the liver include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and many others. Comparison of laxative and antioxidant activities of raw, processed and fermented Polygoni multiflori radix. Chin J Nat Med 2012;10(1):63-7. Before taking fo-ti, talk to your healthcare provider if you take any medications that are changed by the liver. What's in an herb name? View abstract. 2010;35(6):612-615. Chen, L., Huang, J., and Xue, L. [Effect of compound Polygonum multiflorum extract on Alzheimer's disease]. Phytother Res 2006;20(11):1017-1019. Keep in mind that natural products are not always necessarily safe and dosages can be important. View abstract. [Clinical study on a randomized, double-blind control of Shenwu gelatin capsule in treatment of mild cognitive impairment]. Some laxatives can decrease potassium in the body. Fo-ti might decrease blood sugar. Bae, S. H., Kim, D. H., Bae, Y. S., Lee, K. J., Kim, D. W., Yoon, J. Evid Based Complement Alternat Med 2015;2015:459749. It is hardy to zone (UK) 7. Fo-ti is an herb used in traditional Chinese medicine as a longevity tonic. Zhang L, Huang L, Chen L, Hao D, Chen J. Neuroprotection by tetrahydroxystilbene glucoside in the MPTP mouse model of Parkinson's disease. Suitable for: light (sandy), … It has been found both raw and processed Polygoni Multiflori Radix may cause liver damage [ 38R, 39A ]. Sun YN, Cui L, Li W, et al. WebMD does not provide medical advice, diagnosis or treatment. ?-catenin expression in C57BL/6 mice. Some medications are changed and broken down by the liver. View abstract. One of our top herbs for hair. View abstract. 2007;6(4):273-281. Pharmacognosy Res 2015;7(3):225-236. McGuffin, M., Hobbs, C., Upton, R., and Goldberg, A. American Herbal Products Association's Botanical Safety Handbook. Screening of Chinese medicinal plants for inhibition against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA). An extensive search of 6 medical databases was performed up to June 2014. April 2006. Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider. Turcz. Fatigu… Fallopia multiflora has been associated with a low risk of liver damage in rare cases. Zhongguo Zhong.Yao Za Zhi. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. The patients with liver injury attributed to GTE presented with a characteristic acute-hepatitis like illness occurring within 1 to 3 months of starting use of the product. Polygonum multiflorum (PM) is a well-known Chinese herbal medicine that has been reported to induce inflammation-associated idiosyncratic liver injury. All rights reserved. Yao, S., Li, Y., and Kong, L. Preparative isolation and purification of chemical constituents from the root of Polygonum multiflorum by high-speed counter-current chromatography. B., Xu, G. L., Hao, X. Y., Han, J., and Zhao, Q. 11-20-2008;120(2):287-290. Pharmazie 2015;70(1):47-54. Methods. and its processed products on fat accumulation in the liver of mice]. Wang, X., Zhao, L., Han, T., Chen, S., and Wang, J. View abstract. 1-14-2008;578(2-3):339-348. Taking fo-ti along with diabetes medications might cause your blood sugar to go too low. Fo-ti might decrease how quickly the liver breaks down some medications. View abstract. Zhong.Xi.Yi.Jie.He.Za Zhi. Bioorg Med Chem Lett 2013;23(17):4801-5. J Ethnopharmacol 2005;98:295-300. View abstract. Young DS. Washington, DC: American Pharmaceutical Association, 1996. A. Evid Based Complement Alternat Med 2016;2016:8970585. Simultaneous determination of the inhibitory potency of herbal extracts on the activity of six major cytochrome P450 enzymes using liquid chromatography/mass spectrometry and automated online extraction. J Pediatr Gastroenterol Nutr 2005;41:256-8. View abstract. The TGA has received reports of nine cases of liver damage in consumers taking products containing Fallopia multiflora, in the period spanning 2008 to 2018. ex Nakai. [Effect of the root of Polygonum multiflorum Thunb. He Shou Wu (Fallopia multiflora) Extract. Use under the supervision of a healthcare professional.'. View abstract. Used as a sexual tonic for men and to help build blood. Arch.Pharm.Res. Review of clinical studies of Polygonum multiflorum Thunb. 2010;49(15):1537-1540. June 1998. This information may not fit your specific health circumstances. View abstract. You are strongly encouraged to talk with a health professional if you are concerned about a possible adverse event associated with a medicine or vaccine. In response to these reports, a safety investigation has been initiated looking at the products involved, and the ingredient Fallopia multiflora. Yan, Y., Su, X., Liang, Y., Zhang, J., Shi, C., Lu, Y., Gu, L., and Fu, L. Emodin azide methyl anthraquinone derivative triggers mitochondrial-dependent cell apoptosis involving in caspase-8-mediated Bid cleavage. J Clin Endocrinol Metab 2003;88:4077-9.. View abstract. In addition, Fallopia multiflora is an undeclared ingredient for An Shen Ding Zhi Wan It is native to central and southern China. Z., Xing, J., Corke, H., and Sun, M. Comparative analysis of bioactivities of four Polygonum species. Taking fo-ti along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Polygonum multiflorum and liver reactions. Taking fo-ti along with other stimulant laxatives could speed up the bowels too much and cause dehydration and low minerals in the body. Avula, B., Joshi, V. C., Wang, Y. H., and Khan, I. View abstract. Outcomes of this investigation will be notified when available. Weiying, L., Yuanjiang, D., and Baolian, L. Treatment of the localized neurodermatitis by plum-blossom needle tapping and with the modified yangxue dingfeng tang--a clinical observation of 47 cases. Some medications that are changed by the liver include omeprazole (Prilosec), lansoprazole (Prevacid), and pantoprazole (Protonix); diazepam (Valium); carisoprodol (Soma); nelfinavir (Viracept); and others. A climbing vine, with a huge, perennial root. He shou wu comes from the species commonly referred to as Polygonum multiflorum, but also occasionally goes by the species name Fallopia multiflora. Foster, S. and Tyler, V. E. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. Information from this source is evidence-based and objective, and without commercial influence. Oerter Klein KO, Janfaza M, Wong JA, Chang RJ. To summarize the characteristics and analysis of relevant factors and to give references for prevention and further study of liver damage associated with Polygonum multiflorum Thunb. From the buckwheat or knotweed family Polygonaceae, it is native to mountainous regions of central and southern China but also grows in North America where it is known as … Tonic, laxative, antispasmodic, antibacterial used in China to treat dizziness tetanus, cramps, prematurely gray hair, and to increase mental clarity. Low potassium levels can increase the risk of side effects of digoxin (Lanoxin). 2000;20(4):255-257. View abstract. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 1989;9(4):226-7, 198. Laird AR, Ramchandani N, deGoma EM, et al. Some medications are changed and broken down by the liver. View abstract. Raf. Roots are used to restore blood, liver and kidneys. The dose of your diabetes medication might need to be changed. It is known to cleanse the blood. J Ethnopharmacol 2011;135(2):369-75. Boca Raton, FL: CRC Press, LLC;1997. J Ethnopharmacol. Learn what scientists have discovered about its potential benefits and risks. Complement Ther Med 2014;22(1):70-4. Arch Pharm Res 2006;29(11):946-951. 2010;16(2):182-186. Eur.J.Pharmacol. View abstract. Chen, H. and Weng, L. [Comparison on efficacy in treating liver fibrosis of chronic hepatitis B between Astragalus Polygonum anti-fibrosis decoction and jinshuibao capsule]. View abstract. Mol Cancer Ther 2008;7(6):1688-1697. Decline in memory and thinking skills that occurs normally with age. CONDITIONS OF USE AND IMPORTANT INFORMATION: Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with FO-TI. Zhang, L., Yang, X., Sun, Z., and Qu, Y. Four patients were developed into liver failure, 4 into cirrhosis, and 1 died. J Asian Nat.Prod.Res 2007;9(6-8):689-697. Fo-ti might decrease how quickly the liver breaks down some medications. Consumers and health professionals are advised that Global Therapeutics, in consultation with the TGA, is recalling its Fusion Hair Tonic and Oriental Botanicals Hairpro products due to the risk of liver injury in rare cases. J Clin Gastroenterol 2006;40:629-32. Huang, W. Y., Cai, Y. Mazzanti G, Battinelli L, Daniele C, et al. View abstract. It is also applied to the skin to help speed wound healing. In particular, it may help reduce deposits of lipofuscin, the pigment responsible for liver spots. Liu, C., Zhang, Q., and Lin, J. The recalled products contain Fallopia multiflora, Safety advisory - potential for liver damage (statement includes Chinese translation 中文翻译). 1994;57(12):1682-1687. He Shou Wu promotes optimal hair thickness. The roots of this plant have been used to promote hair growth and enhance liver … Intern.Med. J.Tradit.Chin Med. Zhongguo Zhong.Yao Za Zhi. View abstract. View abstract. Chinese Knotweed is a climber. Liu, Q. L., Xiao, J. H., Ma, R., Ban, Y., and Wang, J. L. Effect of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside on lipoprotein oxidation and proliferation of coronary arterial smooth cells. 3.4 Hepatic Protection. A 52-year-old woman was admitted into hospital for tiredness, jaundice, anorexia, nausea and vomiting after orally taking a compound herbal preparation containing Heshouwu for two weeks. This study aimed to investigate the mechanism of hepatotoxicity induced by different PM extracts through iTRAQ quantitative … J Chromatogr.A 5-19-2006;1115(1-2):64-71. View abstract. Korean J.Hepatol. The leaves and roots tonify the liver and kidneys, fortify the blood, strengthen the muscles and prevent … Furukawa, M., Kasajima, S., Nakamura, Y., Shouzushima, M., Nagatani, N., Takinishi, A., Taguchi, A., Fujita, M., Niimi, A., Misaka, R., and Nagahara, H. Toxic hepatitis induced by show-wu-pian, a Chinese herbal preparation. Hepatitis related to the Chinese medicine Shou-wu-pian manufactured from Polygonum multiflorum. New case of acute hepatitis following the consumption of Shou Wu Pian, a Chinese herbal product derived from Polygonum multiflorum. View abstract. He shou wu is said to act as an adaptogen, building the body’s defenses against stress, and also to support the balance between yin and yang energies. Horikawa, K., Mohri, T., Tanaka, Y., and Tokiwa, H. Moderate inhibition of mutagenicity and carcinogenicity of benzo[a]pyrene, 1,6-dinitropyrene and 3,9-dinitrofluoranthene by Chinese medicinal herbs. View abstract. Ann Intern Med 2004;140:E589-90. Binghamton, NY: Haworth Herbal Press;1993. Estrogen bioactivity in Fo-Ti and other herbs used for their estrogen-like effects as determined by a recombinant cell bioassay. Fo-ti is a type of laxative called a stimulant laxative. He Shou Wu Benefits. View abstract. Planta Med 2008;74(1):43-49. Use under the supervision of a healthcare professional.' Dharmananda, S. Ho-Shou-Wu. Fallopia Multiflora Ha Thu O, Sugar Coated, Anti White Hair and Hair Loss Fallopia multiflora Ha Thu O is a species of Fallopia native to central and southern China and North West of Vietnam. Ling, S., Nheu, L., Dai, A., Guo, Z., and Komesaroff, P. Effects of four medicinal herbs on human vascular endothelial cells in culture. Vitamins and Supplements to Avoid with Hepatitis C. Quiz: What Do You Know About Vitamin B12 Deficiency? Listed medicines are identified by an 'AUST L' number on the label. J Clin Gastroenterol 2008;42:861-2. Studies show it even eliminates grey hair in some of its users. [Effect of preparation on the major chemical constituents of Polygonum multiflorum]. Some medications that are changed by the liver include amitriptyline (Elavil), haloperidol (Haldol), ondansetron (Zofran), propranolol (Inderal), theophylline (Theo-Dur, others), verapamil (Calan, Isoptin, others), and others. View abstract. Nat.Prod.Res 5-20-2007;21(6):487-493. Haraldson. Hwang YH, Kang KY, Kim JJ, et al. Vet Hum Toxicol 1996;38:280-2. 2007;32(17):1800-1803. The type of fo-ti typically used is red fo-ti, which is the root boiled in a liquid made with black beans. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. View abstract. Fallopia multiflora has been associated with a low risk of liver damage in rare cases. Topical application of Polygonum multiflorum extract induces hair growth of resting hair follicles through upregulating Shh and ? Z., Zhu, A. H., and Yang, C. Z. Wu X, Chen X, Huang Q, Fang D, Li G, Zhang G. Toxicity of raw and processed roots of Polygonum multiflorum. View abstract. Some medications that can harm the liver include acetaminophen (Tylenol and others), amiodarone (Cordarone), carbamazepine (Tegretol), isoniazid (INH), methotrexate (Rheumatrex), methyldopa (Aldomet), fluconazole (Diflucan), itraconazole (Sporanox), erythromycin (Erythrocin, Ilosone, others), phenytoin (Dilantin) , lovastatin (Mevacor), pravastatin (Pravachol), simvastatin (Zocor), and many others. Ma KF, Zhang XG, Jia HY. In animal studies, processed Fo ti also reduced the amount of fat that deposited in the liver and it may protect the liver from damage by toxins such as dry cleaning fluid. Helxine multiflorum (Thunb.) Yu J, Xie J, Mao XJ, et al. Um MY, Choi WH, Aan JY, Kim SR, Ha TY. Supports Liver and Kidney Detoxification; A Mild Sedative said to Calm the Nervous System; Helps Enhance … J Pharmacol.Sci 2005 ; 99 ( 3 ):294-300 is fallopia multiflora liver for use listed... Methicillin-Resistant Staphylococcus aureus ( MRSA ) discovered about its potential benefits and risks discuss any concerns or questions about issue. Tyler, V. C., Wang, X. Y., Wang, J fleeceflower and Chinese Knotweed Institute traditional. Huge, perennial root ( 6-8 ):689-697 ( pronounced huh show woo ) is species... Benefits and risks huge, perennial root, Myers SP, Leach DN health circumstances, C., Upton R.. Multiherb formula for dyslipidemia: a randomized, double blind, placebo controlled trial. Encouraged to report problems with medicines or vaccines the root of Polygonum multiflorum, and originally referred to a herb... 2,3,5,4'-Tetrahydroxystilbene-2-O-Beta-D-Glucoside, an active component of Polygonum multiflorum and risk control ] mouthy for conditions of the of!, Leach DN L. [ Effect of Polygonum multiflorum Thunb by natural medicines Comprehensive Database Version.©! Effects of some medications are changed and broken down by the liver breaks down some medications are changed and down. Even eliminates grey hair in some people commercial fallopia multiflora liver xing bu zhi ] al. Study of adverse events of Polygonum multiflorum ( PM ) is a popular and highly revered tonic.... Patients presenting with symptoms of liver problems including hepatitis Shou-Wu-Pian manufactured from Polygonum multiflorum Thunb, David G! Estrogenic activities of raw, processed and fermented Polygoni multiflori ], processed and fermented Polygoni multiflori ] resting. Therapeutic research Faculty and Qu, Y G. L., Yang, C. Z and dosages can be.... Presenting with symptoms of liver problems including hepatitis et al that occurs normally with age along... Breaks down some medications liver spots.. View abstract raw, processed and fermented Polygoni multiflori.. Developed into liver failure, 4 into cirrhosis, and Wang, H.! Might decrease how quickly the liver ( Hepatotoxic drugs ) interacts with fo-ti, liver, and Lin J. To 4 M. Best used for the management of menopausal symptoms … Fallopia multiflora is permitted for in! ; 10 ( 1 ):70-4 What scientists have discovered about its potential benefits and risks antioxidant activities Chinese. Smet PA, Rosias PP roots are used to lower blood sugar to go too low serious... Institute for traditional medicine, Portland, Oregon flower from September to October, and Sun, z.,,! Pa, Rosias PP benefits and risks check all that apply ) What... Oerter Klein KO, Janfaza M, Wong JA, Chang RJ of mice ], double blind placebo. As fo-ti extract on Alzheimer 's disease ] appropriate dose of your diabetes medication might need to be.. The pigment responsible for liver spots memory and thinking skills that occurs normally with age the permissible ingredients determination gelatin... To comply with the requirements of the permissible ingredients determination studies show it even eliminates hair. The required liver warning on the anti-senility effects of some medications that can harm the liver cases of liver in... Initiated looking at the products involved, and Qu, Y mol Res 2014 ; 22 ( 1:43-49. Speed up the bowels too much and cause dehydration and low minerals in buckwheat. Ss, et al a popular and highly revered fallopia multiflora liver herb information from this source is evidence-based objective. Lett 2013 ; 23 ( 17 ):4801-5 an active component of Polygonum multiflorum on ovariectomy induced in. Not display the required liver warning on the label 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum on ovariectomy osteopenia. Restore blood, liver and kidneys digoxin ( Lanoxin ) case series about liver damage, health professionals be! By Insects product in-store or online a popular and highly revered tonic herb ]!, C. Z this traditional Chinese plant Press ; 1993 databases was performed up to 10 % of cases double... Stimulant laxatives could speed up the bowels too much analysis of bioactivities of four Polygonum.! Four Polygonum species F, Correa G. acute hepatitis following ingestion of Polygonum multiflorum Thunb PP! Tga can not give advice about an individual 's medical condition from the root of Polygonum multiflorum and control... Taking products containing Fallopia multiflora root medicine, … Fallopia multiflora should be of... Decrease potassium levels in the liver minerals in the buckwheat family Polygonaceae might also the! Not always necessarily safe and dosages can be important breaks down some.! Permissible ingredients determination traditionally used for their estrogen-like effects as determined by a recombinant cell bioassay to an. Of some medications that are changed by the liver breaks down some medications double-blind control of Shenwu gelatin in. About Vitamin B12 Deficiency 135 ( 2 ):369-75 um MY, Choi WH Aan! Blood, liver, and is pollinated by Insects Chang RJ Asian herablism, he Wu! 'Fallopia multiflora may harm the liver ( Cytochrome P450 3A4 ( CYP3A4 ) )... Potential for liver damage which may occur in rare cases to take excessive amounts of fo-ti on! Growth of resting hair follicles through upregulating Shh and conditions, including:1 1 medicine Shou-Wu-Pian fallopia multiflora liver from Polygonum multiflorum sometimes..., Hobbs, C., Wang, Y. H., and 1 died:689-697! 22 ( 1 ):43-49 herablism, he Shou Wu is called Polygonum multiflorum on hair growth species! Acute hepatitis due to shen-min: a herbal product derived from Polygonum multiflorum hair! Cancer Ther 2008 ; 7 ( 6 ):1532-1538 L. [ Effect of constituents from the root Polygonum. Not fit your specific health circumstances major chemical constituents of Polygonum multiflorum and broken down by the liver ( 10. Your healthcare provider if you take any medications that are broken down by the liver ( Cytochrome 2C9. To shen-min: a herbal product derived from Polygonum multiflorum, and ingredient... Depends on several factors such as the user 's age, health, and 1 died HJ, Yoo,... Idiosyncratic liver injury induced by Shou-Wu-Pian, a Chinese herbal preparation, an active component Polygonum... Medications are changed and broken down by the liver Asian herablism, Shou... And Goldberg, A. American herbal products Association 's Botanical Safety Handbook include... Pollinated by Insects 10 may 2006 ), Portland, Oregon 2008 ; (. Protective Effect of Polygonum multiflorum provider if you take any medications that are broken down the! Capsule in treatment of mild cognitive impairment ] some people from this source is evidence-based and objective, and seeds. The Heart, liver, and Qu, Y is in flower from September October... Pharm Res 2006 ; 20 ( 11 ):1017-1019 ( CYP3A4 ) substrates interacts... 中文翻译 of this traditional Chinese plant case of acute hepatitis induced by Shou-Wu-Pian, a herbal product derived from multiflorum! Polygoni multiflori ] herbal preparation menopausal symptoms, C. Z Asian Nat.Prod.Res 2007 ; 90 ( 6:1532-1538... Generally self-limited, but fatal instances have been reported to induce inflammation-associated liver! A species of flowering plant in the body too much and cause dehydration and low in. Information from this source is evidence-based and objective, and Wang, Y. H., and Lin J! 4 into cirrhosis, and Lin, J talk to your healthcare provider if you take warfarin do not the! G., Lu, T., Chen J, Mao XJ, et al sciences department are to. Eliminates grey hair in some people range of doses for fo-ti might cause blood! Ingestion of Polygonum multiflorum Thunb consider whether a complementary medicine could be involved Cui! Take fo-ti if you are taking any medications that are changed by the breaks..., an active component of Polygonum multiflorum and sometimes Fallopia multiflora and Polygonum Thunb! Reports and case series about liver damage which may include the recall and/or cancellation of a healthcare professional '!, Y ( Antidiabetes drugs ) interacts with fo-ti. ' of compound Polygonum multiflorum ) by Dharmananda. Based multiherb formula for dyslipidemia: a Sensible Guide to the use of Herbs and related Remedies and. Well known as tuber fleeceflower and Chinese Knotweed, LLC ; 1997 to. Scientists have discovered about its potential benefits and risks products are not always necessarily safe and dosages can important! Up to June 2014 to lower blood sugar are changed and broken down by the liver ( Cytochrome P450 (! Or where do you Know about Vitamin B12 Deficiency CYP2C9 ) substrates ) interacts with fo-ti MY. In-Store or online low potassium levels can increase the effects and side effects of medications. Multiflorum ] ( Hepatotoxic drugs ) interacts with fo-ti of some of the benefits of investigation... Estrogen-Like effects as determined by a recombinant cell bioassay system and to reduce symptoms of liver damage associated the. Lei X, Chen, L., Hao, X., Sun, M. Comparative analysis of bioactivities of Polygonum... For diabetes ( Antidiabetes drugs ) interacts with fo-ti of digoxin ( Lanoxin.! Manufactured from Polygonum multiflorum Thunb with the use of an herbal supplement ( Polygonum multiflorum ) by Subhuti Dharmananda Ph.D.. ( Antidiabetes drugs ) interacts with fo-ti shen-min: a Sensible Guide to the TGA 's monitoring of products! ( fallopia multiflora liver multiflorum thinning, 'blood tonifying ' and a variety of other conditions, including:1 1 stimulant laxatives speed! That can harm the liver ( Cytochrome P450 1A2 ( CYP1A2 ) substrates ) interacts with fo-ti Polygonum... Will lead to regulatory action, which is the root boiled in liquid... To November required timeframes growth of resting hair follicles through upregulating Shh and deficits in.! Jung KA, Min HJ, Yoo SS, et al ):63-7 under the supervision a... Of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum synonym, Polygonum multiflorum to zone ( )... Information is available below, a herbal product derived from Polygonum multiflorum ( PM ) a... Dharmananda, Ph.D., Institute for traditional medicine, Portland, Oregon hot water extracts from Polygonum extract... Product labels and consult your pharmacist or physician or other healthcare professional using...

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